Description
Endogenous protein building blocks, so-called peptides, play a central role in the body’s metabolism. They signal the body to activate endogenous repair mechanisms in the skin. This finding is used in cosmetics, and peptides are often used in anti-aging products (INCI: as the word ingredient peptide). Peptides are also used for hair care, such as shampoos, conditioners, and conditioners. They penetrate the inner structure of the hair (the cortex) and strengthen the hair. For example, special active ingredient complexes are used in facials, where peptides can be combined with different vitamins such as vitamin B3, provitamin B5, and vitamin E, as well as other care substances. These active ingredient complexes stimulate the slower regeneration of mature skin and strengthen its structure, thereby contributing to a marked reduction in wrinkles. Another group of peptides is also used for the care of mature skin: polycollagen peptides. They are composed of different peptides and collagen fragments that take over the behavior of native collagen fragments in the skin and play an important role in the natural repair process of the skin. In care products, this process is imitated. The result is a reduction in fine lines and wrinkles. Skin tone and elasticity were improved.
Specifications
Apperance: White to off-white powder
Purity(HPLC): ≥98.0%
Single Impurity: ≤2.0%
Acetate Content(HPLC): 5.0%~12.0%
Water Content (Karl Fischer): ≤10.0%
Peptide Content: ≥80.0%
Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.
How To Order?
1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.
2. Order online. Please fill out the order online form.
3. Provide peptide name, CAS No. or sequence, purity and modification if required, quantity, etc. we will provide a quotation within 2 hours.
4. Order conformation by duly signed sales contract and NDA(non disclosure agreement) or confidential agreement.
5. We will continuously update the order progress in time.
6. Peptide delivery by DHL, Fedex or others, and HPLC, MS, COA will be provided along with the cargo.
7. Refund policy will be followed if any discrepancy of our quality or service.
8. After-sale service: If our clients have any questions about our peptide during experiment, please feel free to contact us and we will respond to it in a short time.
All products of the company are only used for scientific research purpose, it’s prohibited to be directly used by any individuals on human body.
FAQ:
Which end is best for my research?
By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.
Which modified labeled polypeptides can be synthesized in Chinese peptide?
Our company provides a variety of modified peptide labeling, such as acetylation, biotin labeling, phosphorylation modification, fluorescence modification, can also be customized according to your special needs.
How do you dissolve polypeptides?
The solubility of polypeptide depends mainly on its primary and secondary structure, the nature of modification label, solvent type and final concentration. If the peptide is insoluble in water, ultrasound can help dissolve it. For basic peptide, it is recommended to dissolve with 10% acetic acid; For acidic peptides, dissolution with 10%NH4HCO3 is recommended. Organic solvents can also be added to insoluble polypeptides. The peptide is dissolved in the least amount of organic solvent (e.g., DMSO, DMF, isopropyl alcohol, methanol, etc.). It is highly recommended that the peptide be dissolved in the organic solvent first and then slowly added to water or other buffer until the desired concentration.
What are the best preservation conditions? How stable is the peptide?
After lyophilized, polypeptide can form fluff or flocculant powder, which can avoid premature degradation of polypeptide. Recommended storage conditions: a. -20℃ storage or dry environment b. Try to avoid repeated freeze-thaw c. Try to avoid storage in solution state (freeze-dried powder can be stored in separate packages for convenience of use) d. If it must be stored in solution, it is recommended to dissolve the peptides in sterile water under weakly acidic conditions and store at -20℃.
How is my peptide transported? What test reports are provided?
All freeze-dried polypeptides are usually stored in special containers of 2 ml or 10ml with original analytical data and synthesis reports containing important information such as sequence, molecular weight, purity, weight, and number of the polypeptide.
What is net weight? What is peptide content?
After lyophilized peptide is generally fluffy and fluff-like, it may still contain trace amounts of water, adsorbed solvents and salts due to the characteristics of peptide itself. This does not mean that the purity of the peptide is not enough, but that the actual content of the peptide is reduced by 10% to 30%. The net weight of the peptide is the actual weight of the peptide minus the water and protonated ions. In order to ensure the concentration of peptide, the non-peptide substances need to be removed from the crude peptide.
How pure can the peptide be?
Our company can provide different purity levels for customers to choose from, from crude to > 99.9% purity. According to customer needs we can provide purity > 99.9% ultra-pure polypeptide.