Mezlocillin has a similar antibacterial spectrum to piperacillin, has better antibacterial activity against Enterobacteriaceae bacteria, and is less effective against Pseudomonas aeruginosa than azlocillin. It is used in medicine for respiratory tract infection and urinary tract infection caused by sensitive bacteria.
Scope of application:
Mecloxacillin is mainly used for bacterial infections of respiratory system, urinary system, digestive system, gynecological and reproductive organs caused by sensitive strains of Gram-negative bacilli such as Escherichia coli, Pseudomonas aeruginosa, Enterobacter, Proteus and so on. For septicemia, purulent meningitis, peritonitis, osteomyelitis, skin and soft tissue infection, ophthalmology and otorhinolaryngology virus infection and other diseases have a good therapeutic effect.
This paper briefly describes mezlocillin and its application
Methicillin sodium is usually administered by vigorous injection or intravenous injection, and intravenous drip is also possible. Adults need 2-6g at a time, and if the infection is severe, it can be increased to 8-12g, and the maximum dose can be increased to 15g. Children can take the drug according to their body weight. This can be increased to 0.3 g/kg for more severe infections. The drug can be taken 2 to 4 times per day by intramuscular injection, and once every 6 to 8 hours by intravenous infusion.
Adverse reactions:
Adverse reactions were rare, including skin rash, hot, retching, abdominal distension, abdominal pain, soft stool, diarrhea, and elevated transaminase. Allergic symptoms such as rashes, itching. “Prolonged bleeding, purpura or mucosal bleeding, leukopenia or agranulocytosis, anemia, or thrombocytopenia are rare.”
Chinese name: Mezlocillin
English name: Mezlocillin
No. : GT-A0054
CAS number: 51481-65-3
Molecular formula: C21H25N5O8S2
Molecular weight: 539.58
Post time: Nov-21-2023