Palmitoyl pentapeptide-4 is commonly used as a base gel for anti-wrinkle firming skin care products
Palmitoyl pentapeptide-4 (pre-2006 palmitoyl pentapeptide-3) is commonly used as a base gel for anti-wrinkle firming skin care products. It is by the Spanish skin care active ingredient manufacturer in 2000 as their own care industry as the active ingredient, palmitoyl pentapeptide-4 is the peptide series of the earliest use and the most widely used polypeptide, domestic and foreign famous brands are mostly used as the key effective ingredient in the anti-wrinkle firming skin care, in many anti-wrinkle firming skin care products often appear in its figure. By increasing collagen through the dermis, it can reverse the aging process by rebuilding the skin from the inside out. Affect collagen, elastic fibers and hyaluronic acid increase, increase skin moisture content and moisture retention, increase skin thickness and reduce fine lines.
Palmitoyl pentapeptide-4 (Pal-lys-thr-Lys-ser =Pal-KTTKS) contains five amino acids linked to 16-carbon aliphatic chains to enhance the permeability of the molecule through the lipid structure of the skin. This is a margarine. Palmitoyl pentapeptide-4 is a messenger peptide that regulates cell viability by interacting with their specific receptors. They activated genes involved in the upgrading of the extracellular matrix and cell proliferation. Palmitoyl pentapeptide-4 has an anti-wrinkle and skin-tightening effect by activating new synthesis of macromolecules in the extracellular matrix.
Action mechanism
In vitro studies found a 212% increase in type I collagen synthesis, a 100% to 327% increase in type IV collagen synthesis, and a 267% increase in hyaluronic acid synthesis. Collagen I is found in a wide range of 19 forms of collagen in the body. Therefore, increasing the total production of collagen I has a significant effect on rebuilding skin. The six-month in vivo study found an average reduction of 17 percent in the depth of fine lines, 68 percent in the surface area of deep fine lines, 51 percent in the surface area of moderate fine lines, and 16 percent in the roughness of skin.
Post time: Apr-28-2023