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Two methods for the removal of peptides from solid-phase resins
Following chemical synthesis of peptides by solid-phase Fmoc, there are many methods of cleavage, and two basic types are now introduced that we commonly use. 1. Strong acid method (TFA) The dry resin was placed into a shake flask and an appropriate amount of scavengers containing was added. (Sca...Read more -
What are the common types of peptide modifications?
Peptides have now become important components in pharmaceutical products and are being produced on a large scale. These peptides are bioactive substances responsible for various cellular functions in living organisms. Peptide modification is an important means to change the backbone structure and...Read more -
Semaglutide, the weight-loss drug, carries a risk of causing hair loss in women
Why are semaglutide users at Higher risk for hair loss? The team suggests several possible mechanisms: 1. Physiological stress associated with rapid weight loss: semaglutide is associated with significant weight loss (average weight loss of 15% in clinical trials) and may trigger telogen effluviu...Read more -
Talk to you about the relationship between peptide bonds and amino acids
From the perspective of contemporary organic chemistry, peptides are a class of chemical substances with 2-50 amino acids linked by peptide bonds. The amino group of an amino acid is condensed with the carboxyl group of another amino acid, and the amide bond converted into a molecule of water is ...Read more -
Study on the effect of sea cucumber peptide on skin care
Sea samplings are the best seafood products known to everyone. Their nutritional composition and efficacy are extremely high. They are one of the eight best seafood products in the world, together with mountain ginseng, flower gum and dried abalone. Sea cucumber peptide is a kind of protein hydro...Read more -
Utility of ularitide in acute heart failure
In patients with acute heart failure, the initial application of arterial vasodilators can reduce the working pressure of the heart wall, reduce the potential myocardial injury, and thus benefit the recovery of patients. Researchers recently studied the use of uraritide in patients with acute hea...Read more -
Sleep-inducing peptide, sleep comes naturally
In 1977, the Schoenenberger-Monnier group in Basel isolated Delta sleep-inducing peptide (DSIP) from rabbit cerebral venous blood and initially used it as a sleep-promoting factor. The main amino acid sequence of DSIP is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu with a molecular weight of 848.8kDa. Del...Read more -
Preliminary understanding of peptide self-assembly research
Molecular self-assembly is ubiquitous in nature and participates in various biological activities to ensure the orderly progress of physiological functions and biochemical reactions of organisms. Peptide self-assembly is an important part of molecular self-assembly, and its excellent biocompatibi...Read more -
Nosopinopeptides are neuropeptides Overview
Nosophodipeptide, the chemical name is n-caproate-tyrosine-isoleucine – (6) aminocaproic acid amide, also known as Dihexa. It is a neuropeptide substance that has the function of regulating brain cell receptors and is mainly used as a neuroprotective agent and a promoter of memory enhanceme...Read more -
Pentapeptide-18 an application in the field of skin care
Basic Information Its English name is Pentapeptide-18 Essence: It is a small molecule peptide composed of 5 amino acids. Mechanism of action Promoting the secretion of neurotransmitter inhibitors: Pentapeptide-18 can stimulate skin cells and enhance the secretion of neurotransmitter inhibitors. T...Read more -
An overview of dipeptide-2
Basic Information CAS: 24587-37-9 Molecular formula: C16H21N3O3 Molecular weight: 303.36 Introduction Dipeptide-2 is a dipeptide composed of two standard amino acids, valine and tryptophan. It can inhibit the angiotensin converting enzyme ACE, enhance the lymphatic circulation of the eye, promote...Read more -
Use of dipeptide-1 in life
Dipeptide-1 is an active peptide with specific physiological functions and is composed of glycine and L-histidine linked by peptide bonds. Glycine is the simplest amino acid with a side chain of only one hydrogen atom. L-histidine, however, carries an imidazolyl side chain, and this structure con...Read more